The destruction of the forests of the Amazon basin imperils global climate stability and the climate-resilience of vulnerable indigenous and local communities. The proposed Program will accelerate the regional shift to a sustainable, low-emissions, climate-resilient development paradigm. Greater regional collaboration and the replication of effective strategies for mitigation and adaptation from key geographies will mobilize increased private-sector investment, facilitate scaling up of innovation and create efficiencies by leveraging technical resources, data, and best practices across countries. The program, working within the framework of the groundbreaking Leticia Pact for the Amazon, will support Bolivia, Brazil, Colombia, Ecuador and Peru to improve management of at least 35M ha of forest, reduce emissions by approximately 31.6 MtCO2eq and increase the resilience of 3.8 million rural and urban inhabitants of target landscapes and support diversified, climate-resilient livelihood options of at least 320,000 vulnerable people.